Article
Investigation of correlation between mutational status in key EGFR signaling genes and prognosis of stage II colorectal cancer.
Future oncology (London, England) - 1 Jul 2017
Li Li, Ni Bei-Bei, Zhong Qing-Hua, Liu Yan-Hui, Zhang Ming-Hui, Zhang Ke-Ping, Chen Dai-Ci, Wang Lei
Abstract excerpt
AIM: To investigate the relationship between mutations of key genes in the EGFR signaling pathway and the prognosis of stage II colorectal cancer patients without chemotherapy. MATERIALS & METHODS: The incidence of KRAS, NRAS, BRAF, PIK3CA mutations and deficient DNA mismatch repair were assessed in 160 stage II colorectal cancer patients who had been treated by radical operation without adjuvant chemotherapy....
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