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Article

Association of BDNF Val66Met Polymorphism and Brain BDNF Levels with Major Depression and Suicide.

The international journal of neuropsychopharmacology - 1 Jun 2018

Youssef Mariam M, Underwood Mark D, Huang Yung-Yu, Hsiung Shu-Chi, Liu Yan, Simpson Norman R, Bakalian Mihran J, Rosoklija Gorazd B, Dwork Andrew J, Arango Victoria, Mann J John

Abstract excerpt

Background: Brain-derived neurotrophic factor is implicated in the pathophysiology of major depressive disorder and suicide. Both are partly caused by early life adversity, which reduces brain-derived neurotrophic factor protein levels. This study examines the association of brain-derived neurotrophic factor Val66Met polymorphism and brain brain-derived neurotrophic factor levels with depression and suicide. We...

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Source

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Identifiers

PMID: 29432620
DOI: 10.1093/ijnp/pyy008
PMCID: PMC6007393

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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