Article
The association between brain-derived neurotrophic factor polymorphism (BDNF Val66Met) and suicide.
Journal of affective disorders - 1 Feb 2011
Pregelj Peter, Nedic Gordana, Paska Alja Videtič, Zupanc Tomaž, Nikolac Matea, Balažic Jože, Tomori Martina, Komel Radovan, Seler Dorotea Muck, Pivac Nela
Abstract excerpt
BACKGROUND: Brain-derived neurotrophic factor (BDNF) mediates neural plasticity, mood, different behaviours, and stress response. A functional BDNF polymorphism (BDNF Val66Met) was reported to influence the effects of stressful life events or childhood adversity on depression and suicidal behaviour in various psychopathologies. The study evaluated the association between BDNF Val66Met variants and suicide,...
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