Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Val66Met polymorphism of the brain-derived neurotrophic-factor gene is associated with geriatric depression.

Neurobiology of aging - 1 Dec 2006

Hwang Jen-Ping, Tsai Shih-Jen, Hong Chen-Jee, Yang Chen-Hong, Lirng Jiing-Feng, Yang Ya-Min

Abstract excerpt

Brain-derived neurotrophic-factor (BDNF), the most abundant of the neurotrophins in the brain, has been implicated in both major depression and cognitive function. This study examines the association between the BDNF-gene Val66Met polymorphism and depression susceptibility and severity, age-of-onset, cognitive function and suicidal attempt history in an elderly Chinese sample population. We genotyped the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Substitution
Share to Brain-Derived Neurotrophic Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Depressive Disorder

Share to Genetic Markers

Share to Methionine

Share to Mutation, Missense

Share to Severity of Illness Index

Share to Valine

Source

Identifiers

PMID: 16343697
DOI: 10.1016/j.neurobiolaging.2005.10.013

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Val66Met polymorphism of the brain-derived neurotrophic-factor gene is associated with geriatric depression.PMID 16343697Read ↗

The brain-derived neurotrophic-factor (BDNF) val66met polymorphism is associated with geriatric depression: a meta-analysis.Semantic proximity Read ↗

Allelic differences in the brain-derived neurotrophic factor Val66Met polymorphism in late-life depression.Semantic proximity Read ↗

Association between BDNF (Val66Met) Gene Polymorphism, Oxidative Stress Biomarkers and Physiological Alterations in Early and Late Onset Geriatric DepressionSemantic proximity Read ↗

The G-712A polymorphism of brain-derived neurotrophic factor is associated with major depression but not schizophrenia.Semantic proximity Read ↗

Hippocampal volumes and the brain-derived neurotrophic factor val66met polymorphism in geriatric major depression.Semantic proximity Read ↗

The brain-derived neurotrophic factor rs6265 (Val66Met) polymorphism and depression in Mexican-Americans.Semantic proximity Read ↗

The BDNF gene Val66Met polymorphism as a modifier of psychiatric disorder susceptibility: progress and controversy.Semantic proximity Read ↗

Depression, the Val66Met polymorphism, age, and gender influence the serum BDNF level.Semantic proximity Read ↗

Association study of a brain-derived neurotrophic-factor genetic polymorphism and major depressive disorders, symptomatology, and antidepressant response.Semantic proximity Read ↗

Role of BDNF Val66Met functional polymorphism in Alzheimer's disease-related depression.Semantic proximity Read ↗

Brain-derived neurotrophic factor and mental disorders.Semantic proximity Read ↗

The brain-derived neurotrophic factor Val66Met polymorphism, hippocampal volume, and cognitive function in geriatric depression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.