Article
BDNF Val66Met polymorphism, life stress and depression: A meta-analysis of gene-environment interaction.
Journal of affective disorders - 1 Feb 2018
Zhao Mingzhe, Chen Lu, Yang Jiarun, Han Dong, Fang Deyu, Qiu Xiaohui, Yang Xiuxian, Qiao Zhengxue, Ma Jingsong, Wang Lin, Jiang Shixiang, Song Xuejia, Zhou Jiawei, Zhang Jian, Chen Mingqi, Qi Dong, Yang Yanjie, Pan Hui
Abstract excerpt
BACKGROUND: Depression is thought to be multifactorial in etiology, including genetic and environmental components. While a number of gene-environment interaction studies have been carried out, meta-analyses are scarce. The present meta-analysis aimed to quantify evidence on the interaction between brain-derived neurotrophic factor (BDNF) Val66Met polymorphism and stress in depression. METHODS: Included were 31...
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