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Article

Role of CD133 Molecule in Wnt Response and Renal Repair

12 Feb 2018

Abstract excerpt

Abstract Renal repair after injury is dependent on clonal expansion of proliferation-competent cells. In the human kidney, the expression of CD133 characterizes a population of resident scattered cells with resistance to damage and ability to proliferate. However, the biological function of the CD133 molecule is unknown. By RNA sequencing, we found that cells undergoing cisplatin damage lost the CD133 signature...

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PMID: 29431914
DOI: 10.1002/sctm.17-0158

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