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Article

Epigenetic Regulation of Cancer Stem Cell Marker Cd133 by Transforming Growth Factor-β

28 Jan 2010

Abstract excerpt

UNLABELLED: Hepatocellular carcinoma (HCC) is the third leading cause of cancer mortality worldwide. CD133, a transmembrane glycoprotein, is an important cell surface marker for both stem cells and cancer stem cells in various tissues including liver. CD133 expression has been recently linked to poor prognosis in HCC patients. CD133+ liver cancer cells are characterized by resistance to chemotherapy,...

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PMID: 20196115
DOI: 10.1002/hep.23544

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