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Article

TRIM28 Is a Novel Regulator of CD133 Expression Associated with Cancer Stem Cell Phenotype.

International journal of molecular sciences - 30 Aug 2022

Kim Yan S, Potashnikova Daria M, Gisina Alisa M, Kholodenko Irina V, Kopylov Arthur T, Tikhonova Olga V, Kurbatov Leonid K, Saidova Aleena A, Tvorogova Anna V, Kholodenko Roman V, Belousov Pavel V, Vorobjev Ivan A, Zgoda Victor G, Yarygin Konstantin N, Lupatov Alexey Yu

Abstract excerpt

CD133 is an extensively studied marker of the most malignant tumor cell population, designated as cancer stem cells (CSCs). However, the function of this glycoprotein and its involvement in cell regulatory cascades are still poorly understood. Here we show a positive correlation between the level of CD133 plasma membrane expression and the proliferative activity of cells of the Caco-2, HT-29, and HUH7 cancer cell...

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Share to AC133 Antigen
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Line, Tumor

Share to Gene Expression Regulation, Neoplastic

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Source

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Identifiers

PMID: 36077272
DOI: 10.3390/ijms23179874
PMCID: PMC9456468

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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