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Article

CD133: molecule of the moment

7 Dec 2007

Abstract excerpt

CD133 (prominin-1) was the first in a class of novel pentaspan membrane proteins to be identified in both humans and mice, and was originally classified as a marker of primitive haematopoietic and neural stem cells. Due to the highly restricted expression of CD133 family molecules on plasma membrane protrusions of epithelial and other cell types, in association with membrane cholesterol, a role in the...

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PMID: 18067118
DOI: 10.1002/path.2283

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