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Article

COMT and GAD1 gene polymorphisms are associated with impaired antisaccade task performance in schizophrenic patients.

European archives of psychiatry and clinical neuroscience - 1 Sept 2018

Kirenskaya Anna V, Storozheva Zinaida I, Gruden Marina A, Sewell Robert D E

Abstract excerpt

Genetic influences modulating executive functions engaging prefrontal cortical brain systems were investigated in 141 male subjects. The effects of variations in two genes implicated in dopamine and GABA activities in the prefrontal cortex: rs4680 (Val158/Met polymorphism of the catechol-o-methyltransferase gene-COMT) and rs3749034 (C/T) substitution in the promoter region of the glutamic acid decarboxylase gene...

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Share to Catechol O-Methyltransferase
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Share to Polymorphism, Single Nucleotide
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Source

Open in PubMed Open full text

Identifiers

PMID: 29429137
DOI: 10.1007/s00406-018-0881-7
PMCID: PMC6096577

Genes

COMT
GAD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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