Article
[Effect of Heterozygosity Loss in HLA Region before Transplantation on HLA Typing in Patients with Leukemia].
Zhongguo shi yan xue ye xue za zhi - 1 Feb 2018
Zhao Jia-Wei, Wang Ji-Ying, Zhang Yan, Li Qing-Hua, Ru Kun, Wang Xiao-Jing
Abstract excerpt
OBJECTIVE: To investigate the effect of loss of heterozygosity(LOH) in HLA region at initial diagnosis and remission of leukemia patient before transplantation on HLA typing. METHODS: The HLA typing was performed in DNA extracted from peripheral blood obtained at diagnosis (Sample 1 and Sample 2) and remission (Sample 3) in one pretransplant male patient with mixedphenotype acute leukemia (MPAL). HLA typing for...
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