Article
[Association between HLA and leukemia in a mixed Brazilian population].
Revista da Associacao Medica Brasileira (1992) - 1 Jan 2000
Barion Lúcia Aparecida, Tsuneto Luiza Tamie, Testa Giuliana Vitoriano, Lieber Sofia Rocha, Persoli Ligia Beatriz Lopes, Marques Silvia Barbosa Dutra, Vigorito Afonso Celso, Aranha Francisco José Penteado, Eid Katia Aparecida Brito, Oliveira Gislaine Borba, Miranda Eliana Cristina Martins, Souza Cármino Antonio de, Visentainer Jeane Eliete Laguila
Abstract excerpt
OBJECTIVE: The main purpose of this study was to investigate the class I HLA antigens and class II HLA allele frequencies in 164 patients with leukemia: 35 patients with ALL (acute lymphoid leukemia), 50 with AML (acute myeloid leukemia) and 78 with CML (chronic myeloid leukemia). METHODS: The genotyping of class I HLA was performed by microlymphocytotoxicity and of class II by PCR-SSP (polymerase chain reaction...
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