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Article

Two cases of acute lymphoid leukemia patients with loss of heterozygosity in HLA region before transplantation.

HLA - 1 Sept 2021

Huang Wenqiu, Xue Song, Zhang Yongping, Liu Fuhong, Wang Jingbo

Abstract excerpt

Leukemia is a complex disease in which mutations and other genomic and epigenomic abnormalities play a role in both its initiation and progression. Acute lymphoid leukemia (ALL) patients with loss of heterozygosity (LOH) in the HLA region before transplantation have been described rarely. In this report, we described two ALL cases with LOH encompassing the HLA, wholly or partly. HLA molecular typing was performed...

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Identifiers

PMID: 34288574
DOI: 10.1111/tan.14372

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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