Article
[A novel single nucleotide polymorphism-based method for quantitative assessment of chimerism after allogeneic stem cell transplantation.].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Feb 2010
Shao Yu, Wang Jian-Min, Gong Sheng-Lan, Cai Zai-Long, Zhang Wei-Ping, Song Xian-Min, Wang Li-Ping
Abstract excerpt
OBJECTIVE: To develop a novel single nucleotide polymorphism (SNP)-PCR based method for quantitative detection of chimerism after allogeneic haemopoietic stem cell transplantation (allo-HSCT), and to explore its feasibility, accuracy and superiority. METHODS: 18 SNP loci were sereened to identify informative markers for detecting chimerism in each donor/recipient pair before transplantation. Then the chimerism...
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