Article
Bone marrow transplant relapse with loss of an allele.
Clinica chimica acta; international journal of clinical chemistry - 1 Jan 2008
Chen Ding-Ping, Tsai Shu-Hui, Tseng Ching-Ping, Wu Tsu-Lan, Chang Pi-Yueh, Sun Chien-Feng
Abstract excerpt
BACKGROUND: Detection of the extent of chimerism after transplantation is an important method for monitoring the engraftment of donor stem cells or diagnosing relapse. METHODS: The AmpFlSTR Identifiler amplification kit (Applied Biosystem, CA) was used to perform STR-PCR for the study of engraftment. RESULTS: At 6 months post-transplantation, the peripheral blood genotype shows a mixture of donor and recipient...
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