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Article

Minimal residual disease (MRD) detection using rearrangement of immunoglobulin/T cell receptor genes in adult patients with acute lymphoblastic leukemia (ALL).

Annals of hematology - 1 Apr 2018

Shahkarami Sepideh, Mehrasa Roya, Younesian Samareh, Yaghmaie Marjan, Chahardouli Bahram, Vaezi Mohammad, Rezaei Nima, Nikbakht Mohsen, Alimoghaddam Kamran, Ghavamzadeh Ardeshir, Tavakkoly-Bazzaz Javad, Ghaffari Seyed H

Abstract excerpt

MRD detection with allele-specific oligonucleotide-quantitative polymerase chain reaction (ASO-qPCR) and using clone-specific immunoglobulin/T cell receptor rearrangements is considered as a powerful prognostic factor in acute lymphoblastic leukemia (ALL). In the present study, we evaluated an ASO-qPCR assay for MRD quantification in peripheral blood (PB) samples of adult patients with ALL. DNA was isolated from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29392424
DOI: 10.1007/s00277-018-3230-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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