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Minimal Residual Disease in Acute Lymphoblastic Leukemia: Technical and Clinical Advances

7 Aug 2019

Abstract excerpt

Introduction. Acute lymphoblastic leukemia (ALL) is the first neoplasm where the assessment of early response to therapy by minimal residual disease (MRD) monitoring has proven to be a fundamental tool to guide therapeutic choices. The most standardized methods to study MRD in ALL are multi-parametric flow cytometry (MFC) and polymerase chain reaction (PCR) amplification-based methods. Emerging technologies hold...

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PMID: 31448230
DOI: 10.3389/fonc.2019.00726

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