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Detection and management of minimal residual disease in acute lymphoblastic leukemia

24 Nov 2014

Abstract excerpt

The detection of minimal residual disease (MRD) has become part of the state-of-the-art diagnostics to guide treatment both in pediatric and adult acute lymphoblastic leukemia (ALL). This applies to the treatment of de novo and recurrent ALL. In high-risk ALL, MRD detection is considered an important tool to adjust therapy before and after hematopoietic stem cell transplantation. Precise quantification and...

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PMID: 25696862
DOI: 10.1182/asheducation-2014.1.244

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