Article
An update on PCR use for minimal residual disease monitoring in acute lymphoblastic leukemia
11 Sept 2017
Abstract excerpt
INTRODUCTION: Acute lymphoblastic leukemia (ALL) is the first neoplasm where the assessment of early response to therapy by minimal residual disease (MRD) monitoring has proven to be a fundamental tool for guiding therapeutic choices. In recent years, thanks to real-time quantitative PCR (qPCR), MRD monitoring has further achieved higher levels of sensitivity and standardization. However, some outstanding issues...
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