Article
Association between single-nucleotide polymorphisms in six hypertensive candidate genes and hypertension among northern Han Chinese individuals.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Dec 2014
Wang Lijuan, Zhang Bei, Li Mei, Li Chuang, Liu Jielin, Liu Ya, Wang Zuoguang, Zhou Jiapeng, Wen Shaojun
Abstract excerpt
Hypertension is one of the leading risk factors for mortality. The renin-angiotensin-aldosterone system (RAAS) is a potent and powerful mediator in the homeostasis of hypertension. Here, the association between six candidate genes, renin, adrenoceptor β3, angiotensinogen, aldosterone synthase, angiotensin II receptor type 1 and angiotensin II receptor type 2, that are related to RAAS and essential hypertension...
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