Article
Associations between potentially functional CORIN SNPs and serum corin levels in the Chinese Han population.
BMC genetics - 19 Dec 2019
Zhang Huan, Mo Xingbo, Qian Qiyu, Zhou Zhengyuan, Zhu Zhengbao, HuangFu Xinfeng, Xu Tan, Wang Aili, Guo Zhirong, Lei Shufeng, Zhang Yonghong
Abstract excerpt
BACKGROUND: Corin is an important convertase involved in the natriuretic peptide system and may indirectly regulate blood pressure. Genetic factors relate to corin remain unclear. The purpose of the current study was to comprehensively examine the associations among CORIN SNPs, methylations, serum corin levels and hypertension. RESULTS: We genotyped 9 tag-SNPs in the CORIN gene and measured serum corin levels in...
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