Article
Sexual Dimorphism in the Selenocysteine Lyase Knockout Mouse.
Nutrients - 31 Jan 2018
Ogawa-Wong Ashley N, Hashimoto Ann C, Ha Herena, Pitts Matthew W, Seale Lucia A, Berry Marla J
Abstract excerpt
Selenium (Se) is an essential micronutrient known for its antioxidant properties and health benefits, attributed to its presence in selenoproteins as the amino acid, selenocysteine. Selenocysteine lyase (Scly) catalyzes hydrolysis of selenocysteine to selenide and alanine, facilitating re-utilization of Se for de novo selenoprotein synthesis. Previously, it was reported that male Scly-/- mice develop increased...
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