Article
Apolipoprotein E receptor-2 (ApoER2) mediates selenium uptake from selenoprotein P by the mouse testis.
The Journal of biological chemistry - 20 Apr 2007
Olson Gary E, Winfrey Virginia P, Nagdas Subir K, Hill Kristina E, Burk Raymond F
Abstract excerpt
Selenium is a micronutrient that is essential for the production of normal spermatozoa. The selenium-rich plasma protein selenoprotein P (Sepp1) is required for maintenance of testis selenium and for fertility of the male mouse. Sepp1 trafficking in the seminiferous epithelium was studied using conventional methods and mice with gene deletions. Immunocytochemistry demonstrated that Sepp1 is present in...
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