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Article

Deletion of selenoprotein P alters distribution of selenium in the mouse.

The Journal of biological chemistry - 18 Apr 2003

Hill Kristina E, Zhou Jiadong, McMahan Wendy J, Motley Amy K, Atkins John F, Gesteland Raymond F, Burk Raymond F

Abstract excerpt

Selenoprotein P (Se-P) contains most of the selenium in plasma. Its function is not known. Mice with the Se-P gene deleted (Sepp(-/-)) were generated. Two phenotypes were observed: 1) Sepp(-/-) mice lost weight and developed poor motor coordination when fed diets with selenium below 0.1 mg/kg, an...

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Identifiers

PMID: 12574155
DOI: 10.1074/jbc.M300755200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12574155-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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