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Unveiling the Molecular Mechanisms Behind Selenium-Related Diseases Through Knockout Mouse Studies

5 Oct 2009

Abstract excerpt

Selenium (Se), in the form of the 21st amino acid selenocysteine, is an integral part of selenoproteins and essential for mammals. While a large number of health claims for Se has been proposed in a diverse set of diseases, little is known about the precise molecular mechanisms and the physiological roles of selenoproteins. With the recent and rigorous application of reverse genetics in the mouse, great strides...

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PMID: 19803749
DOI: 10.1089/ars.2009.2912

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