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Article

Analysis of carboxylesterase 2 transcript variants in cynomolgus macaque liver.

Xenobiotica; the fate of foreign compounds in biological systems - 1 Feb 2019

Uno Yasuhiro, Igawa Yoshiyuki, Tanaka Maori, Ohura Kayoko, Hosokawa Masakiyo, Imai Teruko

Abstract excerpt

Carboxylesterase (CES) is important for the detoxification of a wide range of drugs and xenobiotics. In this study, the hepatic level of CES2 mRNA was examined in cynomolgus macaques used widely in preclinical studies for drug metabolism. Three CES2 mRNAs were present in cynomolgus macaque liver. The mRNA level was highest for cynomolgus CES2A (formerly CES2v3), much lower for cynomolgus CES2B (formerly CES2v1)...

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Identifiers

PMID: 29384423
DOI: 10.1080/00498254.2018.1435927

Genes

CES2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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