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Macaque cytochromes P450: nomenclature, transcript, gene, genomic structure, and function

9 Feb 2011

Abstract excerpt

Monkeys, especially macaques, including cynomolgus (Macaca fascicularis) and rhesus monkeys (Macaca mulatta), are frequently used in drug metabolism studies due to their evolutionary closeness to humans. Recently, numerous cytochrome P450 (P450 or CYP) cDNAs have been identified and characterized in cynomolgus and rhesus monkeys and were named by the P450 Nomenclature Committee. However, recent advances in genome...

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PMID: 21303270
DOI: 10.3109/03602532.2010.549492

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