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Article

Associations between primary tumor RAS, BRAF and PIK3CA mutation status and metastatic site in patients with chemo-resistant metastatic colorectal cancer.

Acta oncologica (Stockholm, Sweden) - 1 Aug 2018

Christensen Troels Dreier, Palshof Jesper Andreas, Larsen Finn Ole, Poulsen Tim Svenstrup, Høgdall Estrid, Pfeiffer Per, Jensen Benny Vittrup, Yilmaz Mette Karen, Nielsen Dorte

Abstract excerpt

BACKGROUND: Several studies have investigated correlations between metastatic pattern and mutation status in patients with colorectal cancer (CRC). However, most of the studies were small and heterogeneously designed and further research is needed to confirm previous results. In this study, we investigated the association between RAS (KRAS or NRAS), BRAF, PIK3CA mutations and metastatic pattern in patients with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29380640
DOI: 10.1080/0284186X.2018.1433322

Genes

BRAF
KRAS
NRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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