Multiplex family with GAD65-Abs neurologic syndromes

Abstract excerpt

OBJECTIVE: Neurologic autoimmune syndromes associated with anti-glutamate acid decarboxylase 65 antibodies (GAD65-Abs) are rare and mostly sporadic. METHODS: We describe a niece and her aunt with GAD65-Abs neurologic syndromes. High-resolution HLA typing of Class I and Class II alleles was performed using next-generation sequencing. RESULTS: The proband had cerebellar ataxia and probable limbic encephalitis...

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