Article
Myelin oligodendrocyte glycoprotein-associated disorders are associated with HLA subtypes in a Chinese paediatric-onset cohort.
Journal of neurology, neurosurgery, and psychiatry - 1 Jul 2020
Sun Xiaobo, Qiu Wei, Wang Jingqi, Wang Shisi, Wang Yuge, Zhong Xiaonan, Liu Chunxin, Cui Chunping, Hong Hai, Yang Hui, Li Xiao-Jing, Lu Zhengqi, Hu Xueqiang, Kermode Allan G, Peng Lisheng
Abstract excerpt
OBJECTIVE: Myelin oligodendrocyte glycoprotein-associated disorders (MOGADs) are a rare new neurological autoimmune disease with unclear pathogenesis. Since a linkage of the disease to the human leucocyte antigen (HLA) has not been shown, we here investigated whether MOGAD is associated with the HLA locus. METHODS: HLA genotypes of 95 patients with MOGADs, assessed between 2016 and 2018 from three academic...
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