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Article

HLA Class I Haplotype in Glutamic Acid Decarboxylase Antibody-Associated Neurological Disease.

European journal of neurology - 1 May 2026

Bai Lin, Ren Haitao, Lu Qiang, Zhang Han, Yu Yang, Yang Zhuo, Yang Xinzhuang, Fan Siyuan, Wan Xinhua, Zhu Yicheng, Guan Hongzhi, Xiao Meng

Abstract excerpt

OBJECT: Glutamic acid decarboxylase antibody-associated neurological disease (GADAND) is a rare autoimmune disorder with elusive immunogenetic underpinnings. We aimed to investigate HLA associations with GADAND susceptibility in a Chinese cohort. METHODS: We performed HLA genotyping at the HLA-A, -B, -C, -DRB1, -DQA1, and -DQB1 loci in 62 Chinese patients with GADAND and compared them with 990 healthy controls....

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Identifiers

PMID: 42112617
DOI: 10.1111/ene.70619
PMCID: PMC13159121

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