Article
Primary DQ effect in the association between HLA and neurological syndromes with anti-GAD65 antibodies.
Journal of neurology - 1 Jul 2020
Muñiz-Castrillo Sergio, Ambati Aditya, Dubois Valérie, Vogrig Alberto, Joubert Bastien, Rogemond Véronique, Picard Geraldine, Lin Ling, Fabien Nicole, Mignot Emmanuel, Honnorat Jérôme
Abstract excerpt
The primary cause of neurological syndromes with antibodies against glutamic acid decarboxylase 65 (GAD65-Ab) is unknown, but genetic predisposition may exist as it is suggested by the co-occurrence in patients and their relatives of other organ-specific autoimmune diseases, notably type 1 diabetes mellitus (T1DM), and by the reports of a few familial cases. We analyzed the human leukocyte antigen (HLA) in 32...
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