Article
Impact of antiretroviral resistance and virological failure on HIV-1 informational entropy.
The Journal of antimicrobial chemotherapy - 1 Apr 2018
Lima Elidamar Nunes de Carvalho, Piqueira José Roberto Castilho, Camargo Michelle, Galinskas Juliana, Sucupira Maria Cecilia, Diaz Ricardo Sobhie
Abstract excerpt
Objectives: The present study investigated the relationship between genomic variability and resistance of HIV-1 sequences in protease (PR) and reverse transcriptase (RT) regions of the pol gene. In addition, we analysed the resistance among 651 individuals presenting antiretroviral virological failure, from 2009 to 2011, in the state of São Paulo, Brazil. Methods: The genomic variability was quantified by using...
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