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Article

Allergic airways disease develops after an increase in allergen capture and processing in the airway mucosa.

Journal of immunology (Baltimore, Md. : 1950) - 1 Nov 2007

von Garnier Christophe, Wikstrom Matthew E, Zosky Graeme, Turner Debra J, Sly Peter D, Smith Miranda, Thomas Jennifer A, Judd Samantha R, Strickland Deborah H, Holt Patrick G, Stumbles Philip A

Abstract excerpt

Airway mucosal dendritic cells (AMDC) and other airway APCs continuously sample inhaled Ags and regulate the nature of any resulting T cell-mediated immune response. Although immunity develops to harmful pathogens, tolerance arises to nonpathogenic Ags in healthy individuals. This homeostasis is thought to be disrupted in allergic respiratory disorders such as allergic asthma, such that a potentially damaging...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17947647
DOI: 10.4049/jimmunol.179.9.5748

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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