Article
The role of airway dendritic cell populations in regulation of T-cell responses to inhaled antigens: atopic asthma as a paradigm.
Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine - 1 Jan 2002
Holt Patrick G
Abstract excerpt
Chronic atopic asthma in adulthood represents the end stage of a disease process that is initiated during the perinatal period, when the naive immune system is first confronted with potentially allergenic airborne antigens. The initial phase involves compartmentalization of immunological memory into either the T-helper (Th)-1 or Th2 cytokine phenotypes, in atopic and nonatopics, respectively, and in a subset of...
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