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Article

Targeted deletion of c-Met in thymic epithelial cells leads to an autoimmune phenotype.

Immunology and cell biology - 1 Feb 2018

Su Min, Hu Rong, Song Yinhong, Liu Yalan, Lai Laijun

Abstract excerpt

Hepatocyte growth factor (HGF) and its receptor c-Met signaling have been implicated in regulating various types of cells including epithelial cells. We have previously reported that c-Met is expressed by thymic epithelial cells (TECs), and that in vivo administration of hybrid cytokines containing IL-7 and the beta- or alpha-chain of HGF significantly increase the number of TECs. In order to study the role of...

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Source

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Identifiers

PMID: 29363160
DOI: 10.1111/imcb.1026
PMCID: PMC5825253

Genes

HGF
TEC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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