Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic and functional characterization of human thymic stromal cell lines.

Cellular and molecular biology (Noisy-le-Grand, France) - 1 Feb 2001

Wakkach A, Chastre E, Bruand C, Cohen-Kaminsky S, Emami S, Gespach C, Berrih-Aknin S

Abstract excerpt

To establish new tools for studying human thymic stromal cells, we transfected adherent cells from a human postnatal thymus using a plasmid encoding SV40 large T antigen. Among the cell lines obtained, we characterized four epithelial cell lines (LT-TEC1 to LT-TEC4) and one thymic myoid cell line (MITC). Several morphological, functional and phenotypic differences were observed between these 2 cell types....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Polyomavirus Transforming
Share to Cell Line, Transformed

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class II

Share to Intercellular Adhesion Molecule-1

Share to Interferon-gamma

Share to Receptors, Cholinergic

Share to Stromal Cells

Share to Thymus Gland

Source

Identifiers

PMID: 11292252

Genes

TEC
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic and functional characterization of human thymic stromal cell lines.PMID 11292252Read ↗

Cultured Human Thymic-Derived Cells Display Medullary Thymic Epithelial Cell Phenotype and FunctionalitySemantic proximity Read ↗

Untransfected and SV40-transfected fetal and postnatal human thymic stromal cells. Analysis of phenotype, cytokine gene expression and cytokine production.Semantic proximity Read ↗

Thymic Epithelial CellsSemantic proximity Read ↗

Non-Epithelial Thymic Stromal Cells: Unsung Heroes in Thymus Organogenesis and T Cell DevelopmentSemantic proximity Read ↗

Non-Epithelial Stromal Cells in Thymus Development and Function.Semantic proximity Read ↗

Human thymic epithelial cells are frequently transformed by retroviral vectors encoding simian virus 40.Semantic proximity Read ↗

Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens.Semantic proximity Read ↗

Novel Combination of Surface Markers for the Reliable and Comprehensive Identification of Human Thymic Epithelial Cells by Flow Cytometry: Quantitation and Transcriptional Characterization of Thymic Stroma in a Pediatric Cohort.Semantic proximity Read ↗

The fibroblast: An emerging key player in thymic T cell selectionSemantic proximity Read ↗

Thymic epithelial cell heterogeneity: TEC by TEC.Semantic proximity Read ↗

Characterization of human thymic epithelial cell surface antigens: phenotypic similarity of thymic epithelial cells to epidermal keratinocytes.Semantic proximity Read ↗

Rat thymic epithelial cells in culture constitutively secrete IL-1 and IL-6.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.