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Article

Thymic epithelial cell heterogeneity: TEC by TEC.

Nature reviews. Immunology - 1 Apr 2020

Kadouri Noam, Nevo Shir, Goldfarb Yael, Abramson Jakub

Abstract excerpt

The generation of a functional T cell repertoire in the thymus is mainly orchestrated by thymic epithelial cells (TECs), which provide developing T cells with cues for their navigation, proliferation, differentiation and survival. The TEC compartment has been segregated historically into two major populations of medullary TECs and cortical TECs, which differ in their anatomical localization, molecular...

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Identifiers

PMID: 31804611
DOI: 10.1038/s41577-019-0238-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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