Article
DNA microarray-based resonance light scattering assay for multiplexed detection of DNA mutation in papillary thyroid cancer.
The Analyst - 12 Feb 2018
Wang Yaoqi, Gao Jiaxue, Meng Xianying, Wang Zhenxin
Abstract excerpt
Highly accurate analysis of single-nucleotide polymorphisms (SNPs) plays an important role in both disease diagnostics and personalized medicine development. In this work, a DNA microarray-based resonance light scattering (RLS) assay has been developed for multiplexed detection of papillary thyroid carcinoma (PTC) related mutation points including BRAFV600E (t1m), NRAS codon 61 (t2m), TERT promoter g.1295228...
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