Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multiplex detection of ctDNA mutations in plasma of colorectal cancer patients by PCR/SERS assay.

Nanotheranostics - 1 Jan 2020

Lyu Nana, Rajendran Vinoth Kumar, Diefenbach Russell J, Charles Kellie, Clarke Stephen J, Engel Alexander, Rizos Helen, Molloy Mark P, Wang Yuling

Abstract excerpt

Molecular diagnostic testing of KRAS and BRAF mutations has become critical in the management of colorectal cancer (CRC) patients. Some progress has been made in liquid biopsy detection of mutations in circulating tumor DNA (ctDNA), which is a fraction of circulating cell-free DNA (cfDNA), but slow analysis for DNA sequencing methods has limited rapid diagnostics. Other methods such as quantitative PCR and more...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Circulating Tumor DNA
Share to Colorectal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HCT116 Cells

Share to Liquid Biopsy

Share to Multiplex Polymerase Chain Reaction

Share to Mutation

Share to Sensitivity and Specificity

Share to Spectrum Analysis, Raman

Source

Open in PubMed Open full text

Identifiers

PMID: 32923312
DOI: 10.7150/ntno.48905
PMCID: PMC7484630

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiplex detection of ctDNA mutations in plasma of colorectal cancer patients by PCR/SERS assay.PMID 32923312Read ↗

Surface Enhanced Raman Spectroscopy (SERS) for the Multiplex Detection of Braf, Kras, and Pik3ca Mutations in Plasma of Colorectal Cancer Patients.Semantic proximity Read ↗

Highly specific detection of KRAS single nucleotide polymorphism by asymmetric PCR/SERS assay.Semantic proximity Read ↗

Simple, Sensitive and Accurate Multiplex Detection of Clinically Important Melanoma DNA Mutations in Circulating Tumour DNA with SERS Nanotags.Semantic proximity Read ↗

Sensitive and Direct DNA Mutation Detection by Surface-Enhanced Raman Spectroscopy Using Rational Designed and Tunable Plasmonic Nanostructures.Semantic proximity Read ↗

Direct Plasmonic Detection of Circulating RAS Mutated DNA in Colorectal Cancer PatientsSemantic proximity Read ↗

Circulating tumor DNA in cancer diagnosis, monitoring, and prognosis.Semantic proximity Read ↗

Direct plasmonic detection of circulating RAS mutated DNA in colorectal cancer patients.Semantic proximity Read ↗

Profiling DNA mutation patterns by SERS fingerprinting for supervised cancer classification.Semantic proximity Read ↗

Liquid biopsy genotyping by a simple lateral flow strip assay with visual detection.Semantic proximity Read ↗

Rapid Multiplex Strip Test for the Detection of Circulating Tumor DNA Mutations for Liquid Biopsy Applications.Semantic proximity Read ↗

Ultrasensitive Detection of Circulating Tumor DNA of Lung Cancer via an Enzymatically Amplified SERS-Based Frequency Shift AssaySemantic proximity Read ↗

Detection of EGFR mutation in plasma using multiplex allele-specific PCR (MAS-PCR) and surface enhanced Raman spectroscopy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.