Article
Surface Enhanced Raman Spectroscopy for DNA Biosensors-How Far Are We?
Molecules (Basel, Switzerland) - 4 Dec 2019
Pyrak Edyta, Krajczewski Jan, Kowalik Artur, Kudelski Andrzej, Jaworska Aleksandra
Abstract excerpt
A sensitive and accurate identification of specific DNA fragments (usually containing a mutation) can influence clinical decisions. Standard methods routinely used for this type of detection are PCR (Polymerase Chain Reaction, and its modifications), and, less commonly, NGS (Next Generation Sequencing). However, these methods are quite complicated, requiring time-consuming, multi-stage sample preparation, and...
Topics
- Biosensing Techniques
- DNA
- Metal Nanoparticles
- Mutation
- Nucleic Acid Conformation
- Spectrum Analysis, Raman