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Validation of a mobile phone-assisted microarray decoding platform for signal-enhanced mutation detection.

Biosensors & bioelectronics - 15 Aug 2011

Zhang Guanbin, Li Caixia, Lu Yuan, Hu Hua, Xiang Guangxin, Liang Zhiqing, Liao Pu, Dai Pu, Xing Wanli, Cheng Jing

Abstract excerpt

We have established a mobile phone-assisted microarray decoding platform for signal-enhanced mutation detection. A large amount of single-stranded DNA (ssDNA) was obtained by combining symmetric PCR and magnetic isolation, and ssDNA prepared with magnetic bead as label was further allowed to hybridize against the tag-array for decoding purpose. High sensitivity and specificity was achieved with the detection of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21676608
DOI: 10.1016/j.bios.2011.05.031

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