Article
Nanoparticles with Raman spectroscopic fingerprints for DNA and RNA detection.
Science (New York, N.Y.) - 30 Aug 2002
Cao YunWei Charles, Jin Rongchao, Mirkin Chad A
Abstract excerpt
Multiplexed detection of oligonucleotide targets has been performed with gold nanoparticle probes labeled with oligonucleotides and Raman-active dyes. The gold nanoparticles facilitate the formation of a silver coating that acts as a surface-enhanced Raman scattering promoter for the dye-labeled particles that have been captured by target molecules and an underlying chip in microarray format. The strategy...
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