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Article

Characterization of the multimeric structure of poly(A)-binding protein on a poly(A) tail.

Scientific reports - 23 Jan 2018

Sawazaki Ryoichi, Imai Shunsuke, Yokogawa Mariko, Hosoda Nao, Hoshino Shin-Ichi, Mio Muneyo, Mio Kazuhiro, Shimada Ichio, Osawa Masanori

Abstract excerpt

Eukaryotic mature mRNAs possess a poly adenylate tail (poly(A)), to which multiple molecules of poly(A)-binding protein C1 (PABPC1) bind. PABPC1 regulates translation and mRNA metabolism by binding to regulatory proteins. To understand functional mechanism of the regulatory proteins, it is necessary to reveal how multiple molecules of PABPC1 exist on poly(A). Here, we characterize the structure of the multiple...

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Identifiers

PMID: 29362417
DOI: 10.1038/s41598-018-19659-6
PMCID: PMC5780489

Genes

PABPC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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