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Article

Dual interactions of the translational repressor Paip2 with poly(A) binding protein.

Molecular and cellular biology - 1 Aug 2001

Khaleghpour K, Kahvejian A, De Crescenzo G, Roy G, Svitkin Y V, Imataka H, O'Connor-McCourt M, Sonenberg N

Abstract excerpt

The cap structure and the poly(A) tail of eukaryotic mRNAs act synergistically to enhance translation. This effect is mediated by a direct interaction of eukaryotic initiation factor 4G and poly(A) binding protein (PABP), which brings about circularization of the mRNA. Of the two recently identified PABP-interacting proteins, one, Paip1, stimulates translation, and the other, Paip2, which competes with Paip1 for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11438674
DOI: 10.1128/MCB.21.15.5200-5213.2001
PMCID: PMC87244

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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