Article
Plasmodium falciparum genetic variation of var2csa in the Democratic Republic of the Congo.
Malaria journal - 24 Jan 2018
Verity Robert, Hathaway Nicholas J, Waltmann Andreea, Doctor Stephanie M, Watson Oliver J, Patel Jaymin C, Mwandagalirwa Kashamuka, Tshefu Antoinette K, Bailey Jeffrey A, Ghani Azra C, Juliano Jonathan J, Meshnick Steven R
Abstract excerpt
BACKGROUND: The Democratic Republic of the Congo (DRC) bears a high burden of malaria, which is exacerbated in pregnant women. The VAR2CSA protein plays a crucial role in pregnancy-associated malaria (PAM), and hence quantifying diversity at the var2csa locus in the DRC is important in understanding the basic epidemiology of PAM, and in developing a robust vaccine against PAM. METHODS: Samples were taken from the...
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