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Article

Genetic Risk Score Is Associated with Vertical Cup-to-Disc Ratio and Improves Prediction of Primary Open-Angle Glaucoma in Latinos.

Ophthalmology - 1 Jun 2018

Nannini Drew R, Kim Heejin, Fan Fangda, Gao Xiaoyi

Abstract excerpt

PURPOSE: Genome-wide association studies have identified multiple genetic variants associated with vertical cup-to-disc ratio (VCDR). Genetic risk scores (GRS) examine the aggregate genetic effect of individual variants on a trait by combining these separate genetic variants into a single measure. The purpose of this study was to construct GRS for VCDR and to determine whether the GRS are associated with VCDR and...

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Source

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Identifiers

PMID: 29361357
DOI: 10.1016/j.ophtha.2017.12.014
PMCID: PMC5963986

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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