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Article

Aggregate Effects of Intraocular Pressure and Cup-to-Disc Ratio Genetic Variants on Glaucoma in a Multiethnic Asian Population.

Ophthalmology - 1 Jun 2015

Tham Yih-Chung, Liao Jiemin, Vithana Eranga N, Khor Chiea-Chuen, Teo Yik-Ying, Tai E-Shyong, Wong Tien Y, Aung Tin, Cheng Ching-Yu

Abstract excerpt

PURPOSE: High intraocular pressure (IOP) and large vertical cup-to-disc ratio (VCDR) are important risk factors of glaucoma. Recent genome-wide association studies have discovered several genetic variants associated with IOP and VCDR. In this study, we examined the aggregate effects of these IOP-, VCDR-associated variants on glaucoma. DESIGN: Case-control genetic association study. PARTICIPANTS: A total of 6881...

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Identifiers

PMID: 25745874
DOI: 10.1016/j.ophtha.2015.01.024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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