Article

Association between Cognitive Function and Large Optic Nerve Cupping, Accounting for Cup-Disc-Ratio Genetic Risk Score

2021-09-30

Abstract excerpt

<h4>Purpose</h4> To investigate if accounting for a cup-to-disc ratio (CDR) genetic risk score (GRS) modified the association between large CDR and cognitive function among women. <h4>Design</h4> This was a retrospective study using data from the Women’s Health Initiative. <h4>Methods</h4> Patients with glaucoma or ocular hypertension were excluded. Large CDR was defined as ≥ 0.6 in either eye. Cognitive functi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 96d3df6a-0cf5-53e1-8968-6bd6db64d268
DOI: 10.1101/2021.09.30.462651

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Association between Cognitive Function and Large Optic Nerve Cupping, Accounting for Cup-Disc-Ratio Genetic Risk ScoreDOI 10.1101/2021.09.30.462651Read

Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process.Semantic proximity Read

Genetic Risk Score Is Associated with Vertical Cup-to-Disc Ratio and Improves Prediction of Primary Open-Angle Glaucoma in Latinos.Semantic proximity Read

Predictive Power of Polygenic Risk Scores for Intraocular Pressure or Vertical Cup-Disc Ratio.Semantic proximity Read

Aggregate Effects of Intraocular Pressure and Cup-to-Disc Ratio Genetic Variants on Glaucoma in a Multiethnic Asian Population.Semantic proximity Read

Large-scale machine-learning-based phenotyping significantly improves genomic discovery for optic nerve head morphology.Semantic proximity Read

Relationships of visual impairment and eye conditions with imaging markers, cognition, and diagnoses of dementia: a bi-directional Mendelian randomization studySemantic proximity Read

Causal association among glaucoma, cerebral cortical structures, and Alzheimer's disease: insights from genetic correlation and Mendelian randomization.Semantic proximity Read

Genetic variants associated with optic nerve vertical cup-to-disc ratio are risk factors for primary open angle glaucoma in a US Caucasian population.Semantic proximity Read

A Genome-Wide Association Study of Vertical Cup-Disc Ratio in a Latino Population.Semantic proximity Read

Clarifying the role of ATOH7 in glaucoma endophenotypes.Semantic proximity Read

A Precise Method to Evaluate 360 Degree Measures of Optic Cup and Disc Morphology in an African American Cohort and Its Genetic Applications.Semantic proximity Read

A genome-wide association study of optic disc parameters.Semantic proximity Read