Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between genetic variants associated with vertical cup-to-disc ratio and phenotypic features of primary open-angle glaucoma.

Ophthalmology - 1 Sept 2012

Mabuchi Fumihiko, Sakurada Yoichi, Kashiwagi Kenji, Yamagata Zentaro, Iijima Hiroyuki, Tsukahara Shigeo

Abstract excerpt

PURPOSE: To assess the association between the genetic variants associated with the optic nerve vertical cup-to-disc ratio (VCDR) and the phenotypic features in patients with primary open-angle glaucoma (POAG), including normal-tension glaucoma (NTG) and high-tension glaucoma (HTG). DESIGN: Case-control study. PARTICIPANTS AND CONTROLS: Japanese patients with NTG (n = 213) and HTG (n = 212) and 191 control...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Vesicular Transport
Share to Basic Helix-Loop-Helix Transcription Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Checkpoint Kinase 2

Share to Cyclin-Dependent Kinase Inhibitor p15

Share to Glaucoma, Open-Angle

Share to Intraocular Pressure

Share to Optic Disk

Share to Optic Nerve Diseases

Source

Identifiers

PMID: 22584021
DOI: 10.1016/j.ophtha.2012.02.044

Genes

CHEK2
ATOH7
DCLK1
SIX1
SCYL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between genetic variants associated with vertical cup-to-disc ratio and phenotypic features of primary open-angle glaucoma.PMID 22584021Read ↗

Genetic variants associated with optic nerve vertical cup-to-disc ratio are risk factors for primary open angle glaucoma in a US Caucasian population.Semantic proximity Read ↗

Genetic associations of variants in 10 glaucoma-related genes with POAG risk and structural phenotypes in Korean subjects.Semantic proximity Read ↗

Genetic Variants Associated With Different Risks for High Tension Glaucoma and Normal Tension Glaucoma in a Chinese Population.Semantic proximity Read ↗

Common genetic variants associated with open-angle glaucoma.Semantic proximity Read ↗

Genetic investigation into the endophenotypic status of central corneal thickness and optic disc parameters in relation to open-angle glaucoma.Semantic proximity Read ↗

New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.Semantic proximity Read ↗

Glaucoma risk alleles at CDKN2B-AS1 are associated with lower intraocular pressure, normal-tension glaucoma, and advanced glaucoma.Semantic proximity Read ↗

A Genome-Wide Association Study of Vertical Cup-Disc Ratio in a Latino Population.Semantic proximity Read ↗

Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process.Semantic proximity Read ↗

Aggregate Effects of Intraocular Pressure and Cup-to-Disc Ratio Genetic Variants on Glaucoma in a Multiethnic Asian Population.Semantic proximity Read ↗

Genetic analysis of Japanese primary open-angle glaucoma patients and clinical characterization of risk alleles near CDKN2B-AS1, SIX6 and GAS7.Semantic proximity Read ↗

Genetic Risk Score Is Associated with Vertical Cup-to-Disc Ratio and Improves Prediction of Primary Open-Angle Glaucoma in Latinos.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.